Synthesis of a Novel Suppressor of β-Cell Apoptosis via Diversity-Oriented Synthesis-Reference-Cited by-同舟云学术

Synthesis of a Novel Suppressor of β-Cell Apoptosis via Diversity-Oriented Synthesis

Published:2011-07-01 Issue:9 Volume:2 Page:698-702
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Chou Danny Hung-Chieh¹,Duvall Jeremy R.¹,Gerard Baudouin¹,Liu Haibo¹,Pandya Bhaumik A.¹,Suh Byung-Chul¹,Forbeck Erin M.¹,Faloon Patrick¹,Wagner Bridget K.¹,Marcaurelle Lisa A.¹

Affiliation:

1. Chemical Biology Program and Chemical Biology Platform, The Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml200120m

Reference24 articles.

1. Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes

2. Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in β-Cells

3. Flavonoids Protect Against Cytokine-Induced Pancreatic β-Cell Damage Through Suppression of Nuclear Factor κB Activation

4. Silymarin Protects Pancreatic β-Cells against Cytokine-Mediated Toxicity: Implication of c-Jun NH2-Terminal Kinase and Janus Kinase/Signal Transducer and Activator of Transcription Pathways

5. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells

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