Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies

Author:

Condon Stephen M.1,Mitsuuchi Yasuhiro1,Deng Yijun1,LaPorte Matthew G.1,Rippin Susan R.1,Haimowitz Thomas1,Alexander Matthew D.1,Kumar Pavan Tirunahari1,Hendi Mukta S.1,Lee Yu-Hua1,Benetatos Christopher A.1,Yu Guangyao1,Kapoor Gurpreet Singh1,Neiman Eric1,Seipel Martin E.1,Burns Jennifer M.1,Graham Martin A.1,McKinlay Mark A.1,Li Xiaochun2,Wang Jiawei2,Shi Yigong2,Feltham Rebecca3,Bettjeman Bodhi4,Cumming Mathew H.4,Vince James E.56,Khan Nufail56,Silke John356,Day Catherine L.4,Chunduru Srinivas K.1

Affiliation:

1. TetraLogic Pharmaceuticals, Inc., 343 Phoenixville Pike, Malvern, Pennsylvania 19355, United States

2. School of Life Science, Tsinghua University, Beijing, 100084, China

3. Department of Biochemistry, La Trobe University, Victoria 3086, Australia

4. Biochemistry Department, University of Otago, Dunedin 9054, New Zealand

5. The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia

6. Department of Medical Biology, University of Melbourne, Parkville, Victoria 3050, Australia

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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