Gambogic Acid Deactivates Cytosolic and Mitochondrial Thioredoxins by Covalent Binding to the Functional Domain-Reference-Cited by-同舟云学术

Gambogic Acid Deactivates Cytosolic and Mitochondrial Thioredoxins by Covalent Binding to the Functional Domain

Published:2012-06-04 Issue:6 Volume:75 Page:1108-1116
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Yang Jing¹²,Li Chenglin³,Ding Li¹²,Guo Qinglong³,You Qidong³,Jin Shaohong⁴

Affiliation:

1. Department of Pharmaceutical Analysis, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China

2. Key Laboratory of Drug Quality Control and Pharmacovigilance, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China

3. State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, People’s Republic of China

4. National Institution for the Control of Pharmaceutical and Biological Products, Beijing 100050, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np300118c

Reference46 articles.

1. Chemistry and Biology of the CagedGarciniaXanthones

2. Caged Garcinia Xanthones: Development Since 1937

3. Absolute Configuration of (−)-Gambogic Acid, an Antitumor Agent

4. Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells

5. Enhanced cytotoxicity of an anti-transferrin receptor IgG3-avidin fusion protein in combination with gambogic acid against human malignant hematopoietic cells: functional relevance of iron, the receptor, and reactive oxygen species

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