Process Research and Large-Scale Synthesis of 4‘‘,6‘‘-Bis((2-fluorophenyl)carbamoyl)hecogenyl β-O-Cellobioside: A Potent Cholesterol Absorption Inhibitor
Author:
Affiliation:
1. Pfizer Inc., Central Research Division, Process Research and Development Department, Eastern Point Road, Groton, Connecticut 06340, and Ramsgate Road, Sandwich, Kent CT13 9NJ, UK
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op9702206
Reference17 articles.
1. Pharmacologic consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin beta-tigogenin cellobioside (CP-88818; tiqueside).
2. Effects of α- and β-tigogenin cellobiosides on cholesterol absorption
3. 11-Ketotigogenin Cellobioside (Pamaqueside): A Potent Cholesterol Absorption Inhibitor in the Hamster
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1. ChemInform Abstract: Process Research and Large-Scale Synthesis of 4′′,6′′-Bis((2-fluorophenyl)carbamoyl)hecogenyl β-O-Cellobioside: A Potent Cholesterol Absorption Inhibitor.;ChemInform;2010-06-20
2. Gram-scale syntheses of the (1 → 3)-linked and (1 → 4)-linked hyaluronan disaccharides;Carbohydrate Research;2004-05
3. Large-scale Synthesis of Carbohydrates for Pharmaceutical Development;Current Organic Chemistry;2001-12-01
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