Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates-Reference-Cited by-同舟云学术

Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates

Published:2014-10-20 Issue:12 Volume:9 Page:2767-2778
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Duim Whitney C.¹,Jiang Yan¹,Shen Koning¹,Frydman Judith¹,Moerner W. E.¹

Affiliation:

1. Department of Chemistry, ‡Department of Applied Physics, and §Department of Biology, Stanford University, Stanford, California 94305, United States

Funder

Stanford University

National Eye Institute

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb500335w

Reference61 articles.

1. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

2. Huntington's disease: from pathology and genetics to potential therapies

3. Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain

4. A toxic monomeric conformer of the polyglutamine protein

5. Identifying polyglutamine protein species in situ that best predict neurodegeneration

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