Co-crystal Structure and Inhibition of Factor Xa by PD0313052 Identifies Structurally Stabilized Active Site Residues of Factor Xa and Prothrombinase
Author:
Affiliation:
1. Pfizer Global Research and Development, Ann Arbor, Michigan 48105
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi0501838
Reference44 articles.
1. Properties of the factor Xa binding site on human platelets.
2. Human prothrombinase complex assembly and function on isolated peripheral blood cell populations.
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Green by Design: Convergent Synthesis, Computational Analyses, and Activity Evaluation of New FXa Inhibitors Bearing Peptide Triazole Linking Units;Pharmaceutics;2021-12-24
2. Inhibition and Binding Kinetics of the Hepatitis C Virus NS3 Protease Inhibitor ITMN-191 Reveals Tight Binding and Slow Dissociative Behavior;Biochemistry;2009-02-11
3. Highly efficacious factor Xa inhibitors containing α-substituted phenylcycloalkyl P4 moieties;Bioorganic & Medicinal Chemistry Letters;2009-01
4. Structure–activity relationships of anthranilamide-based factor Xa inhibitors containing piperidinone and pyridinone P4 moieties;Bioorganic & Medicinal Chemistry Letters;2008-05
5. Comparison of PD0348292, a selective factor Xa inhibitor, to antiplatelet agents for the inhibition of arterial thrombosis;Thrombosis and Haemostasis;2008
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3