Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator
Author:
Affiliation:
1. Department of Molecular Therapeutics, The Scripps Research Molecular Screening Center (SRMSC), The Scripps Research Institute, Scripps Florida, Jupiter, Florida 33458, United States
Publisher
American Chemical Society (ACS)
Subject
Molecular Medicine,General Medicine,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/cb200496y
Reference15 articles.
1. The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2. Suppression of Immune Induction of Collagen-Induced Arthritis in IL-17-Deficient Mice
3. Retinoid-Related Orphan Receptors (RORs): Critical Roles in Development, Immunity, Circadian Rhythm, and Cellular Metabolism
4. T Helper 17 Lineage Differentiation Is Programmed by Orphan Nuclear Receptors RORα and RORγ
5. Structural Basis for Hydroxycholesterols as Natural Ligands of Orphan Nuclear Receptor RORγ
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