Off-Target Effects of MEK Inhibitors
Author:
Affiliation:
1. Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9041, United States
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi4007644
Reference15 articles.
1. The protein kinases ERK1/2 and their roles in pancreatic beta cells
2. Rapid Activation and Nuclear Translocation of Mitogen-activated Protein Kinases in Response to Physiological Concentration of Glucose in the MIN6 Pancreatic β Cell Line
3. The permissive effects of glucose on receptor-operated potentiation of insulin secretion from mouse islets: a role for ERK1/2 activation and cytoskeletal remodelling
4. Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion
5. Extracellularly Regulated Kinases 1/2 (p44/42 Mitogen-Activated Protein Kinases) Phosphorylate Synapsin I and Regulate Insulin Secretion in the MIN6 β-Cell Line and Islets of Langerhans
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