Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors-Reference-Cited by-同舟云学术

Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors

Published:2009-01-22 Issue:12 Volume:48 Page:2661-2674
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Fischmann Thierry O.¹,Smith Catherine K.¹,Mayhood Todd W.¹,Myers Joseph E.¹,Reichert Paul¹,Mannarino Anthony¹,Carr Donna¹,Zhu Hugh¹,Wong Jesse¹,Yang Rong-Sheng¹,Le Hung V.¹,Madison Vincent S.¹

Affiliation:

1. Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi801898e

Reference65 articles.

1. Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

2. The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation

3. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

4. A requirement for extracellular signal-regulated kinase (ERK) function in the activation of AP-1 by Ha-Ras, phorbol 12-myristate 13-acetate, and serum.

5. Transformation of Mammalian Cells by Constitutively Active MAP Kinase Kinase

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