Substitution of Arginine with Proline and Proline Derivatives in Melanocyte-Stimulating Hormones Leads to Selectivity for Human Melanocortin 4 Receptor
Author:
Affiliation:
1. Department of Chemistry, University of Arizona, Tucson, Arizona 85721
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm801300c
Reference95 articles.
1. Studies on the Physiological Functions of the Melanocortin System
2. Melanocortin Receptors: Identification and Characterization by Melanotropic Peptide Agonists and Antagonists
3. Melanocortin Antagonists Define Two Distinct Pathways of Cardiovascular Control by α- and γ-Melanocyte-Stimulating Hormones
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2. Ligands for Melanocortin Receptors: Beyond Melanocyte-Stimulating Hormones and Adrenocorticotropin;Biomolecules;2022-10-01
3. Demonstration of a Common DPhe7 to DNal(2′)7 Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides;Journal of Medicinal Chemistry;2022-04-11
4. Demonstration of a common DPhe7 to DNal(2’)7 peptide ligand antagonist switch for the melanocortin-3 and melanocortin-4 receptors identifies systematic mischaracterization of the pharmacological properties of melanocortin peptides;2022-01-03
5. The melanocortin pathway and energy homeostasis: From discovery to obesity therapy;Molecular Metabolism;2021-06
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