Azepanone-Based Inhibitors of Human and Rat Cathepsin K-Reference-Cited by-同舟云学术

Azepanone-Based Inhibitors of Human and Rat Cathepsin K

Published:2001-03-24 Issue:9 Volume:44 Page:1380-1395
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Marquis Robert W.¹,Ru Yu¹,LoCastro Steven M.¹,Zeng Jin¹,Yamashita Dennis S.¹,Oh Hye-Ja¹,Erhard Karl F.¹,Davis Larry D.¹,Tomaszek Thaddeus A.¹,Tew David¹,Salyers Kevin¹,Proksch Joel¹,Ward Keith¹,Smith Brian¹,Levy Mark¹,Cummings Maxwell D.¹,Haltiwanger R. Curtis¹,Trescher Gudrun¹,Wang Bing¹,Hemling Mark E.¹,Quinn Chad J.¹,Cheng H-Y.¹,Lin Fan¹,Smith Ward W.¹,Janson Cheryl A.¹,Zhao Baoguang¹,McQueney Michael S.¹,D'Alessio Karla¹,Lee Chao-Pin¹,Marzulli Antonia¹,Dodds Robert A.¹,Blake Simon¹,Shing-Mei Hwang, ¹,James Ian E.¹,Gress Catherine J.¹,Bradley Brian R.¹,Lark Michael W.¹,Gowen Maxine¹,Veber Daniel F.¹

Affiliation:

1. Departments of Medicinal Chemistry, Mechanistic Enzymology, Drug Metabolism and Pharmacokinetics, Physical and Structural Chemistry, Structural Biology, Protein Biochemistry, Life-Cycle Management and Drug Delivery Systems, and Bone and Cartilage Biology, GlaxoSmithKline, 709 Swedeland Road, King of Prussia, Pennsylvania 19406

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000481x

Reference63 articles.

1. Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts

2. Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry

3. Proteolytic Activity of Human Osteoclast Cathepsin K

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