Recursive Partitioning for the Prediction of Cytochromes P450 2D6 and 1A2 Inhibition: Importance of the Quality of the Dataset-Reference-Cited by-同舟云学术

Recursive Partitioning for the Prediction of Cytochromes P450 2D6 and 1A2 Inhibition: Importance of the Quality of the Dataset

Published:2006-09-16 Issue:21 Volume:49 Page:6231-6240
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Burton Julien¹,Ijjaali Ismail¹,Barberan Olivier¹,Petitet François¹,Vercauteren Daniel P.¹,Michel André¹

Affiliation:

1. Laboratoire de Physico-Chimie Informatique, Facultés Universitaires Notre-Dame de la Paix, 61 rue de Bruxelles, B-5000 Namur, Belgium, and Aureus-Pharma, 174 quai de Jemmapes, F-75010 Paris, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060267u

Reference37 articles.

1. Can the pharmaceutical industry reduce attrition rates?

2. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The new quinazoline derivative (N-methyl-N-[(thiophen-2-yl)methyl]quinazoline-2,4-diamine) vasodilates isolated mesenteric arteries through endothelium-independent mechanisms and has acute hypotensive effects in Wistar rats;European Journal of Pharmacology;2023-08

2. Computational prediction of cytochrome P450 inhibition and induction;Drug Metabolism and Pharmacokinetics;2020-02

3. Exploring the Chemical Space of Cytochrome P450 Inhibitors Using Integrated Physicochemical Parameters, Drug Efficiency Metrics and Decision Tree Models;Computation;2019-05-24

4. MOLECULAR MODELLING AND MOLECULAR DOCKING STUDIES OF CYP450 INHIBITORS;International Journal of Pharmaceutical Sciences and Research;2018-05-01

5. QSAR/QSPR Modeling in the Design of Drug Candidates with Balanced Pharmacodynamic and Pharmacokinetic Properties;Challenges and Advances in Computational Chemistry and Physics;2017