Endosomal Escapable and Nuclear Localizing Cationic Polyaspartate-Based CRISPR Activation System for Preventing Respiratory Virus Infection by Specifically Inducing Interferon-λ-Reference-Cited by-同舟云学术

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Endosomal Escapable and Nuclear Localizing Cationic Polyaspartate-Based CRISPR Activation System for Preventing Respiratory Virus Infection by Specifically Inducing Interferon-λ

Published:2022-12-12 Issue:50 Volume:14 Page:55376-55391
ISSN:1944-8244
Container-title:ACS Applied Materials & Interfaces
language:en
Short-container-title:ACS Appl. Mater. Interfaces

Author:

Liu Shuang¹²,Deng Shaohui¹,Li Xiaoxia¹,Chen Jifeng¹,Yuan Yaochang²,Zhao Hanjun³,Zhou Jie³^ORCID,Wang Jin⁴,Zhang Hui²,Cheng Du¹^ORCID

Affiliation:

1. Key Laboratory for Polymeric Composite & Functional Materials of Ministry of Education, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou510275, PR China

2. Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou510275, PR China

3. State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong999077, PR China

4. Department of Radiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou510630, PR China

Funder

Innovation and Technology Commission

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

International Joint Research Project of Guangdong Province

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

Link

https://pubs.acs.org/doi/pdf/10.1021/acsami.2c16588

Reference57 articles.

1. A novel coronavirus outbreak of global health concern

2. Pathogen Recognition and Innate Immunity

3. Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

4. Lambda interferons come to light: dual function cytokines mediating antiviral immunity and damage control

5. Type III interferons disrupt the lung epithelial barrier upon viral recognition

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