PEGylation of Phosphatidylglycerol/Docosahexaenoic Acid Hexosomes with d-α-Tocopheryl Succinate Poly(ethylene glycol)2000 Induces Morphological Transformation into Vesicles with Prolonged Circulation Times

Author:

Bor Gizem1,Lin Jen-Hao2,Lin Kui-Yu3,Chen Hung-Chih2,Prajnamitra Ray Putra2,Salentinig Stefan4ORCID,Hsieh Patrick C. H.256ORCID,Moghimi Seyed Moein789ORCID,Yaghmur Anan1ORCID

Affiliation:

1. Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, Copenhagen ØDK-2100, Denmark

2. Institute of Biomedical Sciences, Academia Sinica, Taipei 11511529, Taiwan

3. Department of Life Sciences, Tzu Chi University, Hualien97004, Taiwan

4. Department of Chemistry, University of Fribourg, Chemin du Musée 9, Fribourg1700, Switzerland

5. Department of Medicine and Stem Cell and Regenerative Medicine Center, University of Wisconsin, Madison, Wisconsin53705, United States

6. Institute of Medical Genomics and Proteomics and Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei 10011529, Taiwan

7. School of Pharmacy, Newcastle University, Newcastle upon TyneNE1 7RU, U.K.

8. Translational and Clinical Research Institute, Newcastle University, Newcastle upon TyneNE2 4HH, U.K.

9. Colorado Center for Nanomedicine and Nanosafety, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado80045, United States

Funder

Natur og Univers, Det Frie Forskningsr?d

Teknologi og Produktion, Det Frie Forskningsr?d

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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