(9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a Selective and Orally Active Neuropeptide Y Y5 Receptor Antagonist-Reference-Cited by-同舟云学术

(9S)-9-(2-Hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a Selective and Orally Active Neuropeptide Y Y5 Receptor Antagonist

Published:2008-07-19 Issue:15 Volume:51 Page:4765-4770
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sato Nagaaki¹,Jitsuoka Makoto¹,Shibata Takunobu¹,Hirohashi Tomoko¹,Nonoshita Katsumasa¹,Moriya Minoru¹,Haga Yuji¹,Sakuraba Aya¹,Ando Makoto¹,Ohe Tomoyuki¹,Iwaasa Hisashi¹,Gomori Akira¹,Ishihara Akane¹,Kanatani Akio¹,Fukami Takehiro¹

Affiliation:

1. Tsukuba Research Institute, Merck Research Laboratories, Banyu Pharmaceutical Co., Ltd., Okubo 3, Tsukuba 300-2611, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm8003587

Reference40 articles.

1. Neuropeptide Y—a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide

2. NEUROPEPTIDE Y AND HUMAN PANCREATIC POLYPEPTIDE STIMULATE FEEDING BEHAVIOR IN RATS

3. Neuroreptide Y: Stimulation of feeding and drinking by injection into the paraventricular nucleus