Predicting Phospholipidosis: A Fluorescence Noncell Based in Vitro Assay for the Determination of Drug–Phospholipid Complex Formation in Early Drug Discovery-Reference-Cited by-同舟云学术

Predicting Phospholipidosis: A Fluorescence Noncell Based in Vitro Assay for the Determination of Drug–Phospholipid Complex Formation in Early Drug Discovery

Published:2011-08-19 Issue:18 Volume:83 Page:6980-6987
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Zhou Liping¹,Geraci Gina²,Hess Sloan²,Yang Linhong²,Wang Jianling²,Argikar Upendra²

Affiliation:

1. Chemical and Pharmaceutical Profiling, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

2. Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac200683k

Reference79 articles.

1. Chloroquine-induced phospholipid fatty liver. Measurement of drug and lipid concentrations in rat liver lysosomes.

2. Iatrogenic lysosomal phospholipidosis in human hepatocytes

3. Drug-induced lysosomal disorders in laboratory animals: new substances acting on lysosomes

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