1. Department of Medicinal Chemistry, Institute of Pharmacy, University of Tromsø, N-9037 Tromsø, Norway, Department of Chemistry, University of Tromsø, N-9037 Tromsø, Norway, Department of Pharmaceutics, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark, Department of Pharmaceutical Chemistry, The University of Kansas, Lawrence, Kansas 66047, and Department of Chemistry, Medicinal Chemistry, Göteborg University, SE−412 96 Göteborg, Sweden