Discovery of 4-Aryl-7-Hydroxyindoline-Based P2Y1 Antagonists as Novel Antiplatelet Agents-Reference-Cited by-同舟云学术

Discovery of 4-Aryl-7-Hydroxyindoline-Based P2Y1 Antagonists as Novel Antiplatelet Agents

Published:2014-07-07 Issue:14 Volume:57 Page:6150-6164
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yang Wu¹,Wang Yufeng¹,Lai Amy¹,Qiao Jennifer X.¹,Wang Tammy C.¹,Hua Ji¹,Price Laura A.¹,Shen Hong¹,Chen Xue-qing¹,Wong Pancras¹,Crain Earl¹,Watson Carol¹,Huang Christine S.¹,Seiffert Dietmar A.¹,Rehfuss Robert¹,Wexler Ruth R.¹,Lam Patrick Y. S.¹

Affiliation:

1. Discovery Chemistry, ‡Discovery Biology, and §Pharmaceutical Candidate Optimization, Bristol-Myers Squibb Research, Post Office Box 5400, Princeton, New Jersey 08643-5400, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5006226

Reference33 articles.

1. Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

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4. Identification of the platelet ADP receptor targeted by antithrombotic drugs

5. Structure and Stereochemistry of the Active Metabolite of Clopidogrel

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