Constrained Analogues of Procaine as Novel Small Molecule Inhibitors of DNA Methyltransferase-1-Reference-Cited by-同舟云学术

Constrained Analogues of Procaine as Novel Small Molecule Inhibitors of DNA Methyltransferase-1

Published:2008-03-18 Issue:7 Volume:51 Page:2321-2325
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Castellano Sabrina¹,Kuck Dirk¹,Sala Marina¹,Novellino Ettore¹,Lyko Frank¹,Sbardella Gianluca¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo, 84084 Fisciano (SA), Italy, Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, Via D. Montesano 49, 80131 Napoli, Italy, and Division of Epigenetics, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm7015705

Reference36 articles.

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2. DNA methylation patterns and epigenetic memory

3. GSTP1 CpG Island Hypermethylation Is Responsible for the Absence of GSTP1 Expression in Human Prostate Cancer Cells

4. Hypermethylation of the Human Glutathione S-Transferase-π Gene (GSTP1) CpG Island Is Present in a Subset of Proliferative Inflammatory Atrophy Lesions but Not in Normal or Hyperplastic Epithelium of the Prostate

5. Number of CpG islands and genes in human and mouse.

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