Enantiospecific Synthesis of 3-Fluoromethyl-, 3-Hydroxymethyl-, and 3-Chloromethyl-1,2,3,4-tetrahydroisoquinolines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the α2-Adrenoceptor-Reference-Cited by-同舟云学术

Enantiospecific Synthesis of 3-Fluoromethyl-, 3-Hydroxymethyl-, and 3-Chloromethyl-1,2,3,4-tetrahydroisoquinolines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the α2-Adrenoceptor

Published:1999-10-01 Issue:21 Volume:42 Page:4351-4361
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Grunewald Gary L.¹,Caldwell Timothy M.¹,Li Qifang¹,Dahanukar Vilas H.¹,McNeil Brynn¹,Criscione Kevin R.¹

Affiliation:

1. Department of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66045

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990086a

Reference41 articles.

1. Purification and Properties of Phenylethanolamine-N-methyl Transferase

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