Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation-Reference-Cited by-同舟云学术

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Published:2004-12-21 Issue:2 Volume:48 Page:414-426
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gill Adrian L.¹,Frederickson Martyn¹,Cleasby Anne¹,Woodhead Steven J.¹,Carr Maria G.¹,Woodhead Andrew J.¹,Walker Margaret T.¹,Congreve Miles S.¹,Devine Lindsay A.¹,Tisi Dominic¹,O'Reilly Marc¹,Seavers Lisa C. A.¹,Davis Deborah J.¹,Curry Jayne¹,Anthony Rachel¹,Padova Alessandro¹,Murray Christopher W.¹,Carr Robin A. E.¹,Jhoti Harren¹

Affiliation:

1. Astex Technology, 436 Cambridge Science Park, Milton Road, Cambridge, CB4 0QA, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049575n

Reference40 articles.

1. Biological Control and Refuge Theory

2. MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

3. Efficacy and safety of retreatment with anti–tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease

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