A Practical Synthesis of a PI3K Inhibitor under Noncryogenic Conditions via Functionalization of a Lithium Triarylmagnesiate Intermediate
Author:
Affiliation:
1. Small Molecule Process Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States
2. Health & Crop Sciences Research Laboratory, Sumitomo Chemical Co., Ltd., 3 Utajima, Nishiyodogawa-ku, Osaka 555-0021, Japan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op3002992
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4. Take your PIK: phosphatidylinositol 3-kinase inhibitors race through the clinic and toward cancer therapy
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