Cryptic Cerulenin Rearrangement in Ketosynthase Covalent Inhibition

Author:

Jiang Ziran1,Chen Jeffrey A.1,Mohamed Osama G.23ORCID,Huynh Jennifer1,Chen Aochiu1ORCID,Tripathi Ashootosh24ORCID,La Clair James J.1,Burkart Michael D.1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0358, United States

2. Natural product Discovery Core – Life Sciences Institute, University of Michigan, Mary Sue Coleman Hall, 210 Washtenaw Avenue, Ann Arbor, Michigan 48109, United States

3. Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr el Aini Street, Cairo 11562, Egypt

4. Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, 1600 Huron Parkway, NCRC B520, Ann Arbor, Michigan 48109, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

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