Detection of a Kinetically Competent Compound-I Intermediate in the Vancomycin Biosynthetic Enzyme OxyB-Reference-Cited by-同舟云学术

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Detection of a Kinetically Competent Compound-I Intermediate in the Vancomycin Biosynthetic Enzyme OxyB

Published:2024-07-11 Issue:29 Volume:146 Page:19629-19634
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Nguy Andy K. L.¹^ORCID,Martinie Ryan J.¹²^ORCID,Cai Amanda¹,Seyedsayamdost Mohammad R.¹³^ORCID

Affiliation:

1. Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States

2. Department of Chemistry, Hamilton College, Clinton, New York 13323, United States

3. Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.4c03102

Reference64 articles.

1. Models and Mechanisms of Cytochrome P450 Action

2. Structure and Chemistry of Cytochrome P450

3. Hydrocarbon Hydroxylation by Cytochrome P450 Enzymes

4. Aliphatic hydroxylation via oxygen rebound. Oxygen transfer catalyzed by iron

5. Aliphatic hydroxylation by highly purified liver microsomal cytochrome P-450. Evidence for a carbon radical intermediate

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