Incorporating Synthetic Accessibility in Drug Design: Predicting Reaction Yields of Suzuki Cross-Couplings by Leveraging AbbVie’s 15-Year Parallel Library Data Set-Reference-Cited by-同舟云学术

Incorporating Synthetic Accessibility in Drug Design: Predicting Reaction Yields of Suzuki Cross-Couplings by Leveraging AbbVie’s 15-Year Parallel Library Data Set

Published:2024-05-20 Issue:22 Volume:146 Page:15070-15084
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Raghavan Priyanka¹^ORCID,Rago Alexander J.²^ORCID,Verma Pritha²,Hassan Majdi M.³,Goshu Gashaw M.²,Dombrowski Amanda W.²^ORCID,Pandey Abhishek³,Coley Connor W.¹^ORCID,Wang Ying²^ORCID

Affiliation:

1. Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, Massachusetts 02139, United States

2. Advanced Chemistry Technologies Group, AbbVie, Inc., 1 N Waukegan Rd, North Chicago, Illinois 60064, United States

3. RAIDERS Group, AbbVie, Inc., 1 N Waukegan Rd, North Chicago, Illinois 60064, United States

Funder

Takeda Pharmaceutical Company

Massachusetts Institute of Technology

National Science Foundation

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.4c00098

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