Multicomponent Synthesis of Imidazole-Based Ionizable Lipids for Highly Efficient and Spleen-Selective Messenger RNA Delivery

Author:

Dong Wang1,Li Zhibin1,Hou Tailin1,Shen Yanqiong2,Guo Zixuan1,Su Yi-Tan2,Chen Ziqi1,Pan Huimin1,Jiang Wei1ORCID,Wang Yucai12ORCID

Affiliation:

1. Department of Radiology, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, China

2. Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, 230601, China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

Strategic Priority Research Program of the Chinese Academy of Sciences

Science and Technology Development Fund, Macau SAR

Anhui Provincial Major Science and Technology Project

Anhui Provincial Key Research and Development Project

Young Elite Scientists Sponsorship Program by CAST

Publisher

American Chemical Society (ACS)

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