A Practical Synthesis of a γ-Secretase Inhibitor-Reference-Cited by-同舟云学术

A Practical Synthesis of a γ-Secretase Inhibitor

Published:2007-04-28 Issue:11 Volume:72 Page:4149-4155
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Scott Jeremy P.¹,Lieberman David R.¹,Beureux Olivier M.¹,Brands Karel M. J.¹,Davies Antony J.¹,Gibson Andrew W.¹,Hammond Deborah C.¹,McWilliams Chris J.¹,Stewart Gavin W.¹,Wilson Robert D.¹,Dolling Ulf-H.¹

Affiliation:

1. Department of Process Research, Merck Sharp & Dohme Research Laboratories, Hertford Road, Hoddesdon, Hertfordshire EN11 9BU, U.K., and Department of Process Research, Merck Research Laboratories, P. O. Box 2000, Rahway, New Jersey 07065

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo070407n

Reference48 articles.

1. Secretases as therapeutic targets in Alzheimer’s disease: patents 2000 – 2004

2. Strategies for disease modification in Alzheimer's disease

3. Alzheimer’s disease pathogenesis and therapeutic interventions

4. Future directions in the treatment of Alzheimer’s disease

5. Living with the enemy: a physiological role for the β-amyloid peptide

Cited by 35 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rh-catalyzed asymmetric hydrogenation of allylic sulfones for synthesis of chiral β-ester sulfones;Organic Chemistry Frontiers;2024

2. Synthesis of chiral sulfones via nickel-catalyzed asymmetric hydrogenation;Organic Chemistry Frontiers;2024

3. Regioselective Radical Cascade Cyclizations of Alkyne-Tethered Cyclohexadienones with Chalcogenides under Visible-Light Catalysis;ACS Omega;2023-09-20

4. Rh-Catalyzed Asymmetric Hydrogenation of α-Substituted Alkenyl Sulfones: Highly Chemo- and Enantioselective Access to Chiral Sulfones;Organic Letters;2023-09-13

5. Selective inhibitors of the PSEN1–gamma-secretase complex;Journal of Biological Chemistry;2023-06