Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPARγ-Selective Agonists: Discovery of Reversed Stereochemistry−Activity Relationship-Reference-Cited by-同舟云学术

Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPARγ-Selective Agonists: Discovery of Reversed Stereochemistry−Activity Relationship

Published:2010-12-03 Issue:1 Volume:54 Page:331-341
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ohashi Masao¹,Oyama Takuji²,Nakagome Izumi³,Satoh Mayumi⁴,Nishio Yoshino¹,Nobusada Hiromi¹,Hirono Shuichi³,Morikawa Kosuke²,Hashimoto Yuichi⁵,Miyachi Hiroyuki¹

Affiliation:

1. Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 1-1-1, Tsushima-Naka, Kita-ku, Okayama 700-8530, Japan

2. Institute for Protein Research, Osaka University, 6-2-3, Furuedai, Suita, Osaka 565-0874, Japan

3. School of Pharmaceutical Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan

4. Tumor Therapy Project, The Tokyo Metropolitan Institute of Medical Science, Tokyo Metropolitan Organization for Medical Research, 2-1-6 Kamikitazawa, Setagaya-ku, Tokyo 156-8506, Japan

5. Institute of Molecular and Cellular Biosciences, The University of Tokyo, 1-1-1, Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101233f

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