Experimental and Theoretical Study of the Effect of Active-Site Constrained Substrate Motion on the Magnitude of the Observed Intramolecular Isotope Effect for the P450 101 Catalyzed Benzylic Hydroxylation of Isomeric Xylenes and 4,4‘-Dimethylbiphenyl-Reference-Cited by-同舟云学术

Experimental and Theoretical Study of the Effect of Active-Site Constrained Substrate Motion on the Magnitude of the Observed Intramolecular Isotope Effect for the P450 101 Catalyzed Benzylic Hydroxylation of Isomeric Xylenes and 4,4‘-Dimethylbiphenyl

Published:1998-12-16 Issue:1 Volume:121 Page:41-47
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Audergon Christian¹,Iyer Krishna R.¹,Jones Jeffrey P.¹,Darbyshire John F.¹,Trager William F.¹

Affiliation:

1. Contribution from the Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, Washington 98195, and Department of Chemistry, Washington State University, Pullman, Washington 99164

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja983000w

Reference42 articles.

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