Synthesis and Structure−Activity Relationship of (Lactamylvinyl)cephalosporins Exhibiting Activity against Staphylococci, Pneumococci, and Enterococci

Author:

Heinze-Krauss Ingrid1,Angehrn Peter1,Guerry Philippe1,Hebeisen Paul1,Hubschwerlen Christian1,Kompis Ivan1,Page Malcolm G. P.1,Richter Hans G. F.1,Runtz Valérie1,Stalder Henri1,Weiss Urs1,Wei Chung-Chen1

Affiliation:

1. F. Hoffmann-La Roche Ltd., 4002 Basel, Switzerland, and Hoffmann-La Roche Inc., Nutley, New Jersey 07110

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference26 articles.

1. Cationic Thionitrosyl and Nitrosyl Complexes

2. Aszodi, J.; Chantot, J.F.; d'Ambrieres, G.; Humbert, D. Nouvelles Céphalosporins comportant en position 7 un radical benzyloximino substitué, leur procédé de préparation, leur application comme médicament. (Novel cephalosporins bearing a benzyloximino substituent in position 7, their preparation and application as pharmaceutical.) EP 0 551 034 A2, 1993.

3. Synthesis and biological properties of 3-[()-2-(1,2,3-Thiadiazolyl)ethenyl]-substituted cephalosporins and related compounds: new oral cephalosporins

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