Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase-Reference-Cited by-同舟云学术

Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase

Published:2013-05-29 Issue:5 Volume:57 Page:1902-1913
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Maynard Andrew¹,Crosby Renae M.²,Ellis Byron¹,Hamatake Robert²,Hong Zhi²,Johns Brian A.²,Kahler Kirsten M.¹,Koble Cecilia²,Leivers Anna²,Leivers Martin R.²,Mathis Amanda²,Peat Andrew J.²,Pouliot Jeffrey J.²,Roberts Christopher D.²,Samano Vicente²,Schmidt Rachel M.¹,Smith Gary K.¹,Spaltenstein Andrew²,Stewart Eugene L.¹,Thommes Pia³,Turner Elizabeth M.²,Voitenleitner Christian²,Walker Jill T.²,Waitt Greg¹,Weatherhead Jason²,Weaver Kurt¹,Williams Shawn¹,Wright Lois¹,Xiong Zhiping Z.²,Haigh David³,Shotwell J. Brad²

Affiliation:

1. GlaxoSmithKline, Platform Technology and Science, 5 Moore Drive, Research Triangle Park, North Carolina 27709-3398, United States

2. GlaxoSmithKline, Infectious Diseases Medicines Discovery Unit, 5 Moore Drive, Research Triangle Park, North Carolina 27709-3398, United States

3. GlaxoSmithKline, Infectious Diseases Centre for Excellence for Drug Discovery, Gunnels Wood Road, Stevenage, Hertfordshire SG1 1NY, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400317w

Reference37 articles.

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3. Not boring at all

4. Boron as a platform for new drug design

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