1. Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via Aldo Moro, I-53100 Siena, Italy, Department of Pharmacognosy & Chemistry of Natural Products, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens 15771, Greece, and Department of Animal & Human Physiology, School of Sciences, University of Athens, Panepistimiopolis Zografou, Athens 157 84, Greece