Differences in the Cellular Response and Signaling Pathways between Cisplatin and Monodentate Organometallic Ru(II) Antitumor Complexes Containing a Terphenyl Ligand-Reference-Cited by-同舟云学术

Differences in the Cellular Response and Signaling Pathways between Cisplatin and Monodentate Organometallic Ru(II) Antitumor Complexes Containing a Terphenyl Ligand

Published:2011-04-19 Issue:3 Volume:8 Page:949-957
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Kisova Anna¹,Zerzankova Lenka¹,Habtemariam Abraha²,Sadler Peter J.²,Brabec Viktor³,Kasparkova Jana¹

Affiliation:

1. Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Kralovopolska 135, CZ-61265 Brno, Czech Republic

2. Department of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, United Kingdom

3. Department of Biophysics, Faculty of Sciences, Palacky University, 17. listopadu 12, CZ-77146 Olomouc, Czech Republic

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp200105d

Reference54 articles.

1. DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity

2. Ruthenium polypyridyl complexes and their modes of interaction with DNA: Is there a correlation between these interactions and the antitumor activity of the compounds?

3. Redox-Active Antineoplastic Ruthenium Complexes with Indazole: Correlation of in Vitro Potency and Reduction Potential

4. An Organometallic Protein Kinase Inhibitor Pharmacologically Activates p53 and Induces Apoptosis in Human Melanoma Cells

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