Novel Approaches for Targeting Thymidylate Synthase To Overcome the Resistance and Toxicity of Anticancer Drugs-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Novel Approaches for Targeting Thymidylate Synthase To Overcome the Resistance and Toxicity of Anticancer Drugs

Published:2010-06-08 Issue:18 Volume:53 Page:6539-6549
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Garg Divita¹²,Henrich Stefan¹,Salo-Ahen Outi M. H.¹³,Myllykallio Hannu⁴,Costi Maria P.⁵,Wade Rebecca C.¹

Affiliation:

1. Molecular and Cellular Modeling Group, Heidelberg Institute of Theoretical Studies gGmbH, Heidelberg, Germany

2. Institute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany

3. Department of Biosiences, Biochemistry, Åbo Akademi University, Turku, Finland

4. Laboratoire d'Optique et Biosciences, Ecole Polytechnique, CNRS UMR7645, INSERM U696, Palaiseau, France

5. Dipartimento di Scienze Farmaceutiche, Università degli Studi di Modena e Reggio Emilia, Modena, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901869w

Reference91 articles.

1. Anticancer Antifolates: Current Status and Future Directions

2. Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase

3. Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

4. Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and Anticancer Evaluation of Benzylated Indole Based Alkyl‐Substituted Pyrido[2,3‐d]Pyrimidines Targeting Thymidylate Synthase;ChemistrySelect;2024-04-16

2. Caffeine enhances chemosensitivity to irinotecan in the treatment of colorectal cancer;Phytomedicine;2023-12

3. New thieno[2,3-b]pyridine-fused pyrimidin-4(3H)-ones as potential thymidylate synthase inhibitors: Synthesis, SAR, in vitro and in silico study;Journal of Molecular Structure;2023-06

4. Virtual screening, structure based pharmacophore mapping, and molecular simulation studies of pyrido[2,3-d]pyrimidines as selective thymidylate synthase inhibitors;Journal of Biomolecular Structure and Dynamics;2023-05-08

5. Targeting human thymidylate synthase: Ensemble-based virtual screening for drug repositioning and the role of water;Journal of Molecular Graphics and Modelling;2023-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3