A Systematic Approach to the Optimization of Substrate-Based Inhibitors of the Hepatitis C Virus NS3 Protease: Discovery of Potent and Specific Tripeptide Inhibitors-Reference-Cited by-同舟云学术

A Systematic Approach to the Optimization of Substrate-Based Inhibitors of the Hepatitis C Virus NS3 Protease: Discovery of Potent and Specific Tripeptide Inhibitors

Published:2004-11-20 Issue:26 Volume:47 Page:6584-6594
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Llinàs-Brunet Montse¹,Bailey Murray D.¹,Ghiro Elise¹,Gorys Vida¹,Halmos Ted¹,Poirier Martin¹,Rancourt Jean¹,Goudreau Nathalie¹

Affiliation:

1. Department of Chemistry, Research and Development, Boehringer Ingelheim (Canada) Ltd., 2100 Cunard Street, Laval, Québec, Canada H7S 2G5

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0494523

Reference43 articles.

1. Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

2. Hepatitis C

3. Treatment of chronic hepatitis C with PEGylated interferon and ribavirin

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