Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity-Reference-Cited by-同舟云学术

Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity

Published:2011-04-06 Issue:8 Volume:54 Page:2980-2993
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jorda Radek¹,Havlíček Libor¹²,McNae Iain W.³,Walkinshaw Malcolm D.³,Voller Jiří⁴,Šturc Antonín¹,Navrátilová Jana¹,Kuzma Marek⁵,Mistrík Martin⁶,Bártek Jiří⁶,Strnad Miroslav¹,Kryštof Vladimír¹

Affiliation:

1. Laboratory of Growth Regulators, Faculty of Science, Palacký University and Institute of Experimental Botany ASCR, Šlechtitelů 11, 78371 Olomouc, Czech Republic

2. Isotope Laboratory, Institute of Experimental Botany ASCR, Videnska 1083, 142 20 Prague, Czech Republic

3. Structural Biochemistry Group, University of Edinburgh, Michael Swann Building, King’s Buildings, Edinburgh, EH9 3JR, Scotland

4. Centre of the Region Haná for Biotechnological and Agricultural Research, Faculty of Science, Department of Growth Regulators, Palacký University, Šlechtitelů 11, Olomouc, CZ-783 71, Czech Republic

5. Laboratory of Molecular Structure Characterization, Institute of Microbiology ASCR, Videnska 1083, 142 20 Prague, Czech Republic

6. Laboratory of Genome Integrity and Institute of Molecular and Translational Medicine, Palacký University, Šlechtitelů 11, 78371 Olomouc, Czech Republic

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200064p

Reference81 articles.

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4. Cyclin-Dependent Kinase Inhibitors as Anticancer Drugs

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