Chemical Modification and Biological Evaluation of New Semisynthetic Derivatives of 28,29-Didehydronystatin A1 (S44HP), a Genetically Engineered Antifungal Polyene Macrolide Antibiotic-Reference-Cited by-同舟云学术

Chemical Modification and Biological Evaluation of New Semisynthetic Derivatives of 28,29-Didehydronystatin A1 (S44HP), a Genetically Engineered Antifungal Polyene Macrolide Antibiotic

Published:2008-12-04 Issue:1 Volume:52 Page:189-196
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Preobrazhenskaya Maria N.¹,Olsufyeva Evgenia N.¹,Solovieva Svetlana E.¹,Tevyashova Anna N.¹,Reznikova Marina I.¹,Luzikov Yuryi N.¹,Terekhova Larisa P.¹,Trenin Aleksei S.¹,Galatenko Olga A.¹,Treshalin Ivan D.¹,Mirchink Elena P.¹,Bukhman Vladimir M.¹,Sletta Håvard¹,Zotchev Sergey B.¹

Affiliation:

1. Gause Institute of New Antibiotics, B. Pirogovskaya 11, 119021 Moscow, Russia, Department of Biotechnology, Norwegian University of Science and Technology, 7491 Trondheim, Norway, and SINTEF Materials and Chemistry, SINTEF, 7465 Trondheim, Norway

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800695k

Reference28 articles.

1. Current Status and Future of Antifungal Therapy for Systemic Mycoses

2. The Mechanism of Overcoming Multidrug Resistance (MDR) of Fungi by Amphotericin B and Its Derivatives

3. Biosynthesis of Deoxyamphotericins and Deoxyamphoteronolides by Engineered Strains of Streptomyces nodosus

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