1. Department of Biomedical Engineering, 44 Cummington St., Room 701, Boston University, Boston, Massachusetts 02215, Boston University School of Medicine, 715 Albany Street, Box 86, Boston, Massachusetts 02118, Department of Biology, 5 Cummington St., Boston University, Boston, Massachusetts 02215, and Department of Pharmacology and Experimental Therapeutics, Boston University, Boston, Massachusetts 02118