Rapid, Continuous Solution-Phase Peptide Synthesis: Application to Peptides of Pharmaceutical Interest
Author:
Affiliation:
1. Department of Chemistry, University of Massachusetts, Amherst, Massachusetts 01003-9336, U.S.A., and Biomeasure, Inc., 27 Maple Street, Milford, Massachusetts 01757-3560, U.S.A.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op0202179
Reference20 articles.
1. (Fluoren-9-ylmethoxy)carbonyl (Fmoc) amino acid chlorides. Synthesis, characterization, and application to the rapid synthesis of short peptide segments
2. Rapid continuous peptide synthesis via FMOC amino acid chloride coupling and 4-(aminomethyl)piperidine deblocking
3. Tris(2-aminoethyl)amine as substitute for 4-(aminomethyl)piperidine in the FMOC/polyamine approach to rapid peptide synthesis
4. For general methods of on-resin monitoring of solid-phase syntheses see: Lloyd-Williams, P.; Albericio, F.; Giralt, E.Chemical Approaches to theSynthesis of Peptides and Proteins; CRC Press: Boca Raton, FL, 1997; p 67.
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