1. Departments of Biopharmaceutical Sciences & Pharmaceutical Chemistry, University of California, San Francisco, California, Chemical Engineering and Petroleum Refining Department, Colorado School of Mines, Golden, Colorado, Faculté de Pharmacie, Université de Paris-Sud, Châtenay-Malabry, France, and Department of Pharmacy & Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, U.K.