2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase: Discovery, SAR, Modeling, and Mutagenesis-Reference-Cited by-同舟云学术

2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase: Discovery, SAR, Modeling, and Mutagenesis

Published:2006-01-25 Issue:5 Volume:49 Page:1693-1705
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Koch Uwe¹,Attenni Barbara¹,Malancona Savina¹,Colarusso Stefania¹,Conte Immacolata¹,Di Filippo Marcello¹,Harper Steven¹,Pacini Barbara¹,Giomini Claudia¹,Thomas Steven¹,Incitti Ilario¹,Tomei Licia¹,De Francesco Raffaele¹,Altamura Sergio¹,Matassa Victor G.¹,Narjes Frank¹

Affiliation:

1. Istituto Di Ricerche Di Biologia Molecolare, P. Angeletti S.p.A. (Merck Research Laboratories, Rome), Via Pontina Km 30,600, 00040 Pomezia, Italy, and Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Terling's Park, Harlow, Eastwick Road, Essex, CM20 2QR, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm051064t

Reference73 articles.

1. Epidemiology of Hepatitis C: Geographic Differences and Temporal Trends

2. Hepatitis C Virus Infection

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