Design and Synthesis of Phosphinamide-Based Hydroxamic Acids as Inhibitors of Matrix Metalloproteinases
Author:
Affiliation:
1. Procter and Gamble Pharmaceuticals, Health Care Research Center, 8700 Mason-Montgomery Road, Mason, Ohio 45040, Procter and Gamble, Corporate Research Division, Miami Valley Laboratories, Cincinnati, Ohio 45253
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm980142s
Reference19 articles.
1. Matrix metalloproteinases and their inhibitors in connective tissue remodeling
2. Gene Expression (Collagenase, Tissue Inhibitor of Metalloproteinases, Complement, and HLA–DR) in Rheumatoid Arthritis and Osteoarthritis Synovium. Quantitative Analysis and Effect of Intraarticular Corticosteroids
3. Detection of Stromelysin and Collagenase in Synovial Fluid From Patients with Rheumatoid Arthritis and Posttraumatic Knee Injury
4. Demonstration of tissue collagenase activity in vivo and its relationship to inflammation severity in human gingiva
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