1-[(ω-Aminoalkyl)amino]-4-[N-(ω-aminoalkyl)carbamoyl]-9-oxo-9,10-dihydro- acridines as Intercalating Cytotoxic Agents: Synthesis, DNA Binding, and Biological Evaluation-Reference-Cited by-同舟云学术

1-[(ω-Aminoalkyl)amino]-4-[N-(ω-aminoalkyl)carbamoyl]-9-oxo-9,10-dihydro- acridines as Intercalating Cytotoxic Agents: Synthesis, DNA Binding, and Biological Evaluation

Published:1997-11-01 Issue:23 Volume:40 Page:3749-3755
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Antonini Ippolito¹,Polucci Paolo¹,Jenkins Terence C.¹,Kelland Lloyd R.¹,Menta Ernesto¹,Pescalli Nicoletta¹,Stefanska Barbara¹,Mazerski Jan¹,Martelli Sante¹

Affiliation:

1. Department of Chemical Sciences, University of Camerino, Via S. Agostino 1, 62032 Camerino, Italy, Cancer Research Campaign Biomolecular Structure Unit and Cancer Research Campaign Cancer Therapeutics Centre, The Institute of Cancer Research, Cotswold Road, Sutton, Surrey SM2 5NG, U.K., Boehringer Mannheim Italia, Research Center, 20052 Monza, Italy, and Department of Pharmaceutical Technology and Biochemistry, Technical University of Gdansk, 80952 Gdansk, Poland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970114u

Reference35 articles.

1. N-[[5-(Trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]-N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor

2. 2-(Aminoalkyl)-5-nitropyrazolo[3,4,5-kl]acridines, a new class of anticancer agents

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