Interaction of Cardiac Troponin C and Troponin I with W7 in the Presence of Three Functional Regions of Cardiac Troponin I
Author:
Affiliation:
1. CIHR Group in Protein Structure and Function, Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2H7
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi060779a
Reference37 articles.
1. Interplay of Troponin- and Myosin-Based Pathways of Calcium Activation in Skeletal and Cardiac Muscle: The Use of W7 as an Inhibitor of Thin Filament Activation
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1. Discovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays;Scientific Reports;2023-03-30
2. Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7;ACS Chemical Biology;2022-06-01
3. A Potent Fluorescent Reversible-Covalent Inhibitor of Cardiac Muscle Contraction;ACS Medicinal Chemistry Letters;2021-08-23
4. The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers;ACS Chemical Biology;2020-07-07
5. Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin;Biochemistry;2018-10-30
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