Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization-Reference-Cited by-同舟云学术

Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization

Published:2006-11-30 Issue:26 Volume:49 Page:7697-7710
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Whiting Matthew¹,Tripp Jonathan C.¹,Lin Ying-Chuan¹,Lindstrom William¹,Olson Arthur J.¹,Elder John H.¹,Sharpless K. Barry¹,Fokin Valery V.¹

Affiliation:

1. Departments of Chemistry and Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060754%2B

Reference28 articles.

1. Overview of the effectiveness of triple combination therapy in antiretroviral-naive HIV-1 infected adults

2. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

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