Autonomous Feedback-Driven Engineered DNAzyme-Coated Trojan Horse-like Nanocapsules for On-Demand CRISPR/Cas9 Delivery-Reference-Cited by-同舟云学术

Autonomous Feedback-Driven Engineered DNAzyme-Coated Trojan Horse-like Nanocapsules for On-Demand CRISPR/Cas9 Delivery

Published:2024-05-16 Issue:21 Volume:18 Page:13950-13965
ISSN:1936-0851
Container-title:ACS Nano
language:en
Short-container-title:ACS Nano

Author:

Tang Xiaoqi¹,Chen Yihui²,Wang Binpan¹,Luo Dan³^ORCID,Wang Jue¹,He Yuan¹,Feng Liu¹^ORCID,Xu Ying⁴,Xie Shuang¹,Chen Ming¹⁵^ORCID,Chang Kai¹^ORCID

Affiliation:

1. Department of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), 30 Gaotanyan, Shapingba, Chongqing 400038, China

2. Department of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, China

3. Department of Biological and Environmental Engineering, Cornell University, Ithaca New York 14853-5701, United States

4. Department of Clinical Laboratory Medicine, School of Clinical Medicine & The First Affiliated Hospital of Chengdu Medical College, Chengdu 610500, China

5. College of Pharmacy and Laboratory Medicine, Third Military Medical University (Army Medical University), 30 Gaotanyan, Shapingba, Chongqing 400038, China

Funder

Chongqing Municipal Science and Technology Bureau

Chongqing Municipal Health Commission

Science Fund for Distinguished Young Scholars of Chongqing Municipality

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsnano.4c04147

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5. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity