Transformation of a Viral Capsid from Nanocages to Nanotubes and Then to Hydrogels: Redirected Self-Assembly and Effects on Immunogenicity

Author:

Yang Mengsi12,Rao Guibo1,Li Long3,Qi Linlin4,Ma Chun12,Zhang Hui12,Gong Jun12,Wei Bin5,Zhang Xian-En6,Chen Guosong3ORCID,Cao Sheng12ORCID,Li Feng12ORCID

Affiliation:

1. State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan 430071, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

3. State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science, Fudan University, Shanghai 200433, China

4. Institute of Geriatrics, Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China

5. Shanghai Engineering Research Center of Organ Repair, School of Life Sciences, Shanghai University, Shanghai 200444, China

6. Faculty of Synthetic Biology, Shenzhen Institute of Advanced Technology, Shenzhen 518055, China

Funder

National Key Research and Development Program of China

Wuhan Science and Technology Project

National Natural Science Foundation of China

Knowledge Innovation Program of Wuhan

Publisher

American Chemical Society (ACS)

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