Coassembly Nanomedicine Mediated by Intermolecular Interactions Between Methotrexate and Baricitinib for Improved Rheumatoid Arthritis Treatment

Author:

Xiong Hehe1,Zhang Heng1,Qin Yatong1,Ye Jinmin1,Zeng Fantian1,Xie Peng1,Shi Changrong1,Luo Changyuan1,Xu Weizhuo1,Yu Chunyang23ORCID,Zhou Zijian1ORCID,Chen Xiaoyuan4567ORCID

Affiliation:

1. State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361102, China

2. School of Chemistry & Chemical Engineering, Frontiers Science Center for Transformative Molecules, Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University, Shanghai 200240, China

3. Key Laboratory of Green and High-end Utilization of Salt Lake Resources, Chinese Academy of Sciences, Xining 810008, China

4. Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, Biomedical Engineering, Yong Loo Lin School of Medicine and College of Design and Engineering, National University of Singapore, Singapore 117597, Singapore

5. Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore

6. Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore

7. Institute of Molecular and Cell Biology, Agency for Science, Technology, and Research (A*STAR), Biopolis Drive, Proteos, Singapore 138673, Singapore

Funder

National Medical Research Council

Ministry of Education - Singapore

China Postdoctoral Science Foundation

Natural Science Foundation of Fujian Province

National Research Foundation Singapore

Science, Technology and Innovation Commission of Shenzhen Municipality

National University of Singapore

National Natural Science Foundation of China

Xiamen University

Publisher

American Chemical Society (ACS)

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