1. Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg SE-412 96, Sweden
2. Department of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg SE-412 96, Sweden
3. DMPK, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg S-431 83, Sweden