Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications

Author:

Sheridan Anastasia12ORCID,Nellenbach Kimberly12,Pandit Sanika12,Byrnes Elizabeth1,Hardy Grace12,Lutz Halle23,Moiseiwitsch Nina12,Scull Grant12,Mihalko Emily124,Levy Jerrold H.5,Brown Ashley C.126ORCID

Affiliation:

1. Joint Department of Biomedical Engineering of University of North Carolina, Chapel Hill and North Carolina State University, Raleigh, North Carolina 27695, United States

2. Comparative Medicine Institute, North Carolina State University, Raleigh, North Carolina 27606, United States

3. Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, North Carolina 27607, United States

4. Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

5. Departments of Anesthesiology, Critical Care, and Surgery, Duke University School of Medicine, Durham, North Carolina 27710, United States

6. Department of Material Science and Engineering, North Carolina State University, Raleigh, North Carolina 27606, United States

Funder

U.S. Department of Health and Human Services

National Science Foundation

Grifols

Publisher

American Chemical Society (ACS)

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